发明名称 |
Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry |
摘要 |
Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay. |
申请公布号 |
US8084269(B2) |
申请公布日期 |
2011.12.27 |
申请号 |
US201113165685 |
申请日期 |
2011.06.21 |
申请人 |
HOLMQUIST BRETT;CLARKE NIGEL;QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
发明人 |
HOLMQUIST BRETT;CLARKE NIGEL |
分类号 |
G01N24/00 |
主分类号 |
G01N24/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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