发明名称 |
Purification of vaccinia viruses using hydrophobic interaction chromatography |
摘要 |
The present invention relates to methods for purification of Vaccinia viruses (VV) and/or Vaccinia virus (VV) particles, which can lead to highly pure and stable virus preparations of predominantly biologically active viruses. The invention encompasses purifying a virus preparation in a sterilized way with high efficiency and desirable yield in terms of purity, biological activity and stability, aspects advantageous for industrial production.
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申请公布号 |
US8163531(B2) |
申请公布日期 |
2012.04.24 |
申请号 |
US201113214979 |
申请日期 |
2011.08.22 |
申请人 |
POST HANSEN SARA;FABER RENE;REICHL UDO;WOLFF MICHAEL;GRAM ANDERS PETER;BAVARIAN NORDIC A/S;OTTO-VON-GUERICKE-UNIVERSITAET;SARTORIUS STEDIM BIOTECH GMBH |
发明人 |
POST HANSEN SARA;FABER RENE;REICHL UDO;WOLFF MICHAEL;GRAM ANDERS PETER |
分类号 |
C12N7/02;A61K39/295 |
主分类号 |
C12N7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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