| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for efficiently and inexpensively producing a compound represented by formula (IV) (preferably an optically active substance) in an industrial scale without using ozone oxidation or a strongly toxic reagent and without requiring optical resolution. <P>SOLUTION: The compound (IV) is produced by reacting a compound (I) with a compound (II) in the presence of an optionally substituted cyclic secondary amine to obtain a compound (III) and sequentially or simultaneously eliminating the protective groups (R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>) of the hydroxy groups of the compound (III), and then cyclizing the R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>-eliminated compound. (In formulas, R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>are each independently a protective group of a hydroxy group). <P>COPYRIGHT: (C)2012,JPO&INPIT |
