发明名称 |
A PROCESS FOR DETERGENT-FREE PRODUCTION OF OUTER MEMBRANE VESICLES OF A GRAM-NEGATIVE BACTERIUM |
摘要 |
The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent-free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines, to OMV obtainable by said process, and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response. |
申请公布号 |
CA2840096(A1) |
申请公布日期 |
2013.01.10 |
申请号 |
CA20122840096 |
申请日期 |
2012.07.05 |
申请人 |
DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS |
发明人 |
VAN DE WATERBEEMD, BAS;VAN DER POL, LEONARDUS ALDOLFUS |
分类号 |
A61K39/095;A61P39/04 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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