发明名称 |
PYRIDINYL- AND PYRAZINYL-METHYLOXY-ARYL DERIVATIVES USEFUL AS INHIBITORS OF SPLEEN TYROSINE KINASE (SYK) |
摘要 |
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory diseases and/or allergic conditions, in cancer therapy, specifically heme malignancies, and autoimmune conditions. |
申请公布号 |
US2014005177(A1) |
申请公布日期 |
2014.01.02 |
申请号 |
US201214004388 |
申请日期 |
2012.03.08 |
申请人 |
ATKINSON FRANCIS LOUIS;BARKER MICHAEL DAVID;LIDDLE JOHN;WILSON DAVID MATTHEW;GLAXO GROUP LIMITED |
发明人 |
ATKINSON FRANCIS LOUIS;BARKER MICHAEL DAVID;LIDDLE JOHN;WILSON DAVID MATTHEW |
分类号 |
C07D401/12;A61K31/4725;A61K31/55;A61K45/06;C07D401/14;C07D403/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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