发明名称 |
PLASMA ANALYTES PREDICT DIAGNOSIS AND PROGNOSIS OF THORACIC AORTIC ANEURYSM |
摘要 |
<p>Disclosed are methods and materials for assessing thoracic aortic aneurysm using a combination of protein and microRNA biomarkers. The presence or levels of the biomarkers can be measured in a body fluid, such as plasma and serum, or in cardiac tissue, to predict the presence and severity of TAA in a subject. This can be used to diagnose and monitor TAA, providing early detection of a lethal and silent disease, as well as reduce the frequency of radiological procedures, which are costly and potentially dangerous.</p> |
申请公布号 |
WO2014004889(A2) |
申请公布日期 |
2014.01.03 |
申请号 |
WO2013US48280 |
申请日期 |
2013.06.27 |
申请人 |
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT |
发明人 |
IKONOMIDIS, JOHN, S.;JONES, JEFFREY A.;RUPAK, MUKHERJEE;STROUD, ROBERT E.;ZILE, MICHAEL R. |
分类号 |
A61K49/04;A61K49/06;A61K49/08 |
主分类号 |
A61K49/04 |
代理机构 |
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代理人 |
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地址 |
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