| 发明名称 |
Diazo bicyclic Smac mimetics and the uses thereof |
| 摘要 |
The invention relates to diazo bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis. |
| 申请公布号 |
US8664212(B2) |
申请公布日期 |
2014.03.04 |
| 申请号 |
US201213557804 |
申请日期 |
2012.07.25 |
| 申请人 |
WANG SHAOMENG;PENG YUEFENG;SUN HAIYING;CAI QIAN;NIKOLOVSKA-COLESKA ZANETA;LU JIANFENG;QIU SU;THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WANG SHAOMENG;PENG YUEFENG;SUN HAIYING;CAI QIAN;NIKOLOVSKA-COLESKA ZANETA;LU JIANFENG;QIU SU |
| 分类号 |
A61K31/33;C07D245/04;C07D487/02 |
主分类号 |
A61K31/33 |
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