| 摘要 |
<p>Provided are a TRPA1 active inhibitor that can relieve irritation of the skin and mucous membranes, and an irritation relieving agent for the skin or mucous membranes. This TRPA1 active inhibitor and irritation relieving agent for the skin or mucous membranes have as an active ingredient a compound represented by the following formula (1). (In the formula, R1 and R2 may be the same or different and represent a hydrogen atom or C1-3 alkyl group, or R1 and R2 may be united and form a cyclohexane ring together with a carbon chain to which these bond; R3 and R4 may be the same or different and represent a hydrogen atom or C1-3 alkyl group (however, in the event that R1 and R2 are united and form a cyclohexane ring together with a carbon chain to which these bond, R3 and R4 both represent hydrogen atoms); R5 represents a C1-6 alkyl group; and R6 represents a hydrogen atom or acyl group. The double line composed of a broken line and a solid line is a single bond or double bone, and in the case of a single bond, indicates that only R4 is present.)</p> |
