摘要 |
<p>The present invention relates to 1-phenyl-substituted heterocyclyl derivatives of the formula (I), wherein X, Y, Z, n, R1, R2, R3, R4, R5, R6, R7 and R10 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.</p> |
申请人 |
ACTELION PHARMACEUTICALS LTD. |
发明人 |
AISSAOUI, HAMED;BOSS, CHRISTOPH;POTHIER, JULIEN;RICHARD-BILDSTEIN, SYLVIA;RISCH, PHILIPPE;SIEGRIST, ROMAIN;FRETZ, HEINZ |