| 发明名称 |
COMPOSITIONS AND METHODS FOR MODULATION OF FGFR3 EXPRESSION |
| 摘要 |
Disclosed are oligonucleotides which target and hybridize to nucleic acid molecules encoding FGFR3, leading to reduced expression of FGFR3. Reduction in the aberrant expression of FGFR3 is beneficial for the treatment of certain medical disorders, such as achondroplasia. |
| 申请公布号 |
EP2922955(A1) |
申请公布日期 |
2015.09.30 |
| 申请号 |
EP20130795243 |
申请日期 |
2013.11.25 |
| 申请人 |
ROCHE INNOVATION CENTER COPENHAGEN A/S |
发明人 |
HEDTJÄRN, MAJ;OTTOSEN, SØREN |
| 分类号 |
C12N15/113;A61K31/7125;C07H21/00 |
主分类号 |
C12N15/113 |
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