Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

摘要

The invention relates to implants which are based on a biodegradable thixotropic compound having pseudoplastic properties and which can be injected subcutaneously or intradermally into the fibrous tissue. The inventive implant comprises microparticles of at least one biocompatible ceramic compound which are suspended in a vector fluid containing at least one hyaluronic acid-based compound and at least one biodegradable thixotropic compound having pseudoplastic properties. The invention also relates to a kit for the extemporaneous use of such implants, the production of said implants and the use thereof in order to fill wrinkles and/or fine lines and/or cutaneous depressions and/or scars.

主权项

1. A resorbable implant for subcutaneous or intradermal injection into fibrous tissue, comprising microparticles of one biocompatible ceramic compound in suspension in at least one vector fluid,
wherein said microparticles are biodegradable, once the implantation has been made into the fibrous tissue, within a period of from 2 to 36 months and have a size of from 10 to 80 μm said ceramic compound is tricalcium phosphate (βTCP) and has a specific surface area of from 0.5 m2/g to 100 m2/g, and said vector fluid comprises at least one compound based on hyaluronic acid and at least one biodegradable thixotropic compound with pseudoplastic properties.