| 发明名称 | Sclerostin antibody crystals and formulations thereof | ||
| 摘要 | Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals. | ||
| 申请公布号 | US9145457(B2) | 申请公布日期 | 2015.09.29 |
| 申请号 | US201214006010 | 申请日期 | 2012.03.23 |
| 申请人 | AMGEN INC. | 发明人 | Clogston Christi L.;Christian Twinkle R.;Osslund Timothy David;Freeman Elisabeth |
| 分类号 | C07K16/22;A61K39/395;A61K39/00 | 主分类号 | C07K16/22 |
| 代理机构 | Marshall, Gerstein & Borun LLP | 代理人 | Marshall, Gerstein & Borun LLP |
| 主权项 | 1. A crystal of an anti-sclerostin IgG antibody comprising two mature light chains each comprised of SEQ ID NO: 13 and two mature heavy chains each comprised of SEQ ID NO: 15, wherein said crystals have a length of up to 500 μm and a shape selected from the group consisting of ellipsoids, rods and needles or mixtures thereof. | ||
| 地址 | Thousand Oaks CA US | ||