| 发明名称 | Compositions and methods for diagnosing and treating an inflammation | ||
| 摘要 | An isolated polypeptide is provided. The polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein the antigen recognition domain comprises at least three CDR amino acid sequences selected from the group consisting of SEQ ID NO: 11, 15, 19, 23, 27 and 31. Also provided are compositions which comprise the peptide and uses of same. | ||
| 申请公布号 | US9145460(B2) | 申请公布日期 | 2015.09.29 |
| 申请号 | US201313913587 | 申请日期 | 2013.06.10 |
| 申请人 | RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES | 发明人 | Karin Nathan;Anunu Rachel;Wildbaum Gizi;Zohar Yaniv;Netzer Nir |
| 分类号 | A61K38/00;A61K39/00;A61K39/395;C07K16/28;G01N33/68 | 主分类号 | A61K38/00 |
| 代理机构 | Pearl Cohen Zedek Latzer Baratz LLP | 代理人 | Pearl Cohen Zedek Latzer Baratz LLP |
| 主权项 | 1. A method of treating an inflammatory disease in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein said antigen recognition domain comprises CDR amino acid sequences as set forth in SEQ ID NO: NO: 11, 15, 19, 23, 27 and 31, thereby treating the inflammatory disease in the subject. | ||
| 地址 | Haifa IL | ||