| 发明名称 | Conjugate comprising P21 protein for the treatment of cancer | ||
| 摘要 | The P21 protein is used as a medicament in the treatment of cancer. A conjugate comprises a first region comprising the P21 protein, or a homologue or functional fragment thereof; and a second region comprising a translocation factor. | ||
| 申请公布号 | US9145446(B2) | 申请公布日期 | 2015.09.29 |
| 申请号 | US200912608718 | 申请日期 | 2009.10.29 |
| 申请人 | Trojan Technologies, Ltd. | 发明人 | Epenetos Agamemnon;Kousparou Christina |
| 分类号 | A61K6/00;A61K38/00;A61K38/16;A61K47/00;A61K47/30;C07K14/435;A61K31/337;A61K31/513;A61K31/555;A61K33/24;A61K38/17;A61K45/06;C07K14/47;A61K47/48 | 主分类号 | A61K6/00 |
| 代理机构 | DLA Piper LLP (US) | 代理人 | DLA Piper LLP (US) |
| 主权项 | 1. A method for the treatment of cancer, comprising administering to a subject in need thereof, a conjugate comprising: a) a first region consisting of a protein having the amino acid sequence as set forth in SEQ ID NO:1; b) a second region comprising the homeodomain of antennapedia; and c) a covalent linker. | ||
| 地址 | London GB | ||