| 发明名称 |
GOLD(I) COMPLEXES WITH T-BUTYL PHOSPHINE AND DIALKYL DITHIOCARBAMATE LIGANDS |
| 摘要 |
Gold(I) complexes of formulae [Au{P(t-Bu)3}(S2CN(CH3)2)] (1), and [Au{P(t-Bu)3}(S2CN(C2H5)2)] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu)3}(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocarbamate complexes show in vitro cytotoxic activities against A549 (human lung carcinoma), HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines. |
| 申请公布号 |
US2015266909(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201414219794 |
申请日期 |
2014.03.19 |
| 申请人 |
King Abdulaziz City for Science and Technology ;King Fahd University of Petroleum and Minerals |
发明人 |
Isab Anvarhusein Abdulkadir;Altaf Muhammad;Monim-ul-Mehboob Muhammad;Seliman Adam Ahmed Abdallah;Wazeer Mohammed Ismail |
| 分类号 |
C07F9/50;G01N33/50 |
主分类号 |
C07F9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A linear gold complex:
Au{P(t-Bu)3}(S2CN(CH3)2. |
| 地址 |
Riyadh SA |
