发明名称 |
METHODS FOR PREDICTING ACUTE REJECTION IN HEART RECIPIENTS |
摘要 |
<p>The present invention relates to method for predicting acute rejection in heart recipients. In particular, the present invention relates to a method for predicting acute rejection in a heart recipient comprising the steps consisting of i) determining the expression level (ELi) of at least one miRNAi selected from the group consisting of miR-155, miR-10a, miR-92a and miR-31 in a blood sample obtained from the heart recipient, ii) comparing the expression level (ELi) determined at step i) with a predetermined reference level (ELRi) and iii) and concluding that the recipient has a high risk of developing acute rejection when the level the expression level (ELi) determined at step i) is different (higher or lower) than the predetermined reference level (ELRi).</p> |
申请公布号 |
WO2015140165(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
WO2015EP55553 |
申请日期 |
2015.03.17 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);UNIVERSITÉ PARIS DIDEROT - PARIS 7;UNIVERSITÉ PARIS DESCARTES;ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) |
发明人 |
DUONG VAN HUYEN, JEAN-PAUL;JOUVEN, XAVIER;LOUPY, ALEXANDRE;TIBLE, MARION |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|