Detection of circulating ADAMTS13-antibody complexes
摘要
<p>The present invention relates to methods and means for detecting ADAMTS13 immune complexes in a sample. The methods include the steps of capturing and labelling immune complexes of anti-ADAMTS13 antibodies. Capturing and labelling may be achieved by two different binding units targeting the immune complexes. The invention further relates to diagnosing diseases associated with immunologic ADAMTS13 dysfunction like TTP (thrombotic thrombocy-topenic purpura).</p>
申请公布号
AU2012255027(B2)
申请公布日期
2015.09.24
申请号
AU20120255027
申请日期
2012.05.18
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A.
发明人
FERRARI, SILVIA;GRUBER, BERNADETTE;PLAIMAUER, BARBARA;ROTTENSTEINER, HANSPETER;SCHEIFLINGER, FRIEDRICH