USE OF TOLL-LIKE RECEPTOR AND TOLL-LIKE AGONIST FOR TREATING CANCER

摘要

PROBLEM TO BE SOLVED: To provide use of toll-like receptor and toll-like agonist for treating cancer.SOLUTION: The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin, resulting in a cis and in-trans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-&kgr;B apoptosis pathway.