Polymorphs of azabicyclohexane

摘要

The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms.

主权项

1. A method for the treatment of depression in a patient in need of said treatment comprising administering to said patient an effective amount of polymorph form A of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane hydrochloride substantially free of other geometric and optical isomers and polymorphic forms thereof.