发明名称 |
SOLUBLE IMMUNOREACTIVE TREPONEMA PALLIDUM TPN47 ANTIGENS TPH47 |
摘要 |
<p>The invention concerns soluble variants of Treponema pallidum antigen 47 (TpN47 antigen) comprising at least domain B, or at least domains A and B, optionally domain D of the complete TpN47 protein molecule with the proviso that all antigens lack domain C (amino acid residues 224 to 351) of TpN47. Moreover, the invention covers DNA encoding the antigens, a method of producing these antigens as well as the use of these antigens in an immunodiagnostic assay for the detection of antibodies against Treponema pallidum in an isolated sample.</p> |
申请公布号 |
HK1202126(A1) |
申请公布日期 |
2015.09.18 |
申请号 |
HK20150102657 |
申请日期 |
2015.03.16 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FAATZ, ELKE;SCHAARSCHMIDT, PETER;SCHMITT, URBAN;SCHOLZ, CHRISTIAN |
分类号 |
C07K;C12N |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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