COMBINED SAMPLE EXAMINATIONS

摘要

The invention relates to a method and an apparatus (1000) for the examination of a sample, for example a slice of biological tissue (11) on a microscope slide (10). The method comprises the generation of an image (I) of the sample (11), the analysis of said image with respect to at least one sample-parameter, the selection of an image-ROI (region of interest) (RI) in said image (I), and the isolation of a corresponding sample-ROI (RS) from the sample (11). Molecular assays are then executed with the isolated sample-ROI (RS), and the data obtained from these assays are linked to the sample-parameter. The sample-parameter may particularly relate to the local amount of a particular cell-type or tissue-type.

主权项

1. A method for the examination of a sample, said method comprising the following steps:
a) generation of a digital image (I) of the sample; b) analyzing said digital image with respect to at least one sample-parameter; c) selection of a region of interest (RI) in said digital image (I); d) isolation of a region of interest (RS) from the sample that corresponds to the selected region of interest in said digital image; e) execution of a molecular assay with the region of interest isolated from the sample to obtain assay-data; f) linking assay-data to the sample-parameter of the corresponding sample region in order that the assay-data and said digital image are simultaneously accessible.