发明名称 |
Method for producing polyploidized megakaryocyte and platelets |
摘要 |
An object of the present invention is to provide a method of promoting polynucleation of megakaryocytic cells to form polynucleated megakaryocytic cells with higher polynucleation, and to provide a method for efficiently producing platelets from polynucleated megakaryocytic cells. The present invention is a method for producing polynucleated megakaryocytic cells, wherein the method includes a step for inducing forced expression of an apoptosis suppressor gene in megakaryocytic cells prior to polynucleation and culturing of these cells. |
申请公布号 |
AU2012256880(B2) |
申请公布日期 |
2015.09.17 |
申请号 |
AU20120256880 |
申请日期 |
2012.05.11 |
申请人 |
THE UNIVERSITY OF TOKYO |
发明人 |
ETO, KOJI;NAKAUCHI, HIROMITSU;TAKAYAMA, NAOYA;NAKAMURA, SOU |
分类号 |
C12N5/10;A61K35/14;A61P7/00;C12N15/09 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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