发明名称 |
MACROCYCLIC TGF-BR2 KINASE INHIBITORS |
摘要 |
The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of Transforming Growth Factor beta Receptor 2 (TGF-β R2) and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of TGF-β R2 -kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent. |
申请公布号 |
WO2015136073(A1) |
申请公布日期 |
2015.09.17 |
申请号 |
WO2015EP55294 |
申请日期 |
2015.03.13 |
申请人 |
ONCODESIGN SA |
发明人 |
HOFLACK, JAN MARIE CYRIEL JOZEF;BERTHET, CYRIL;BENDERITTER, PASCAL ANDRÉ RENÉ;BLOM, PETRA MARCELLA FRANÇOISE;GOMEZ, SYLVIE;DAOUBI, MOURAD |
分类号 |
A61K31/519;A61P19/04 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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