发明名称 |
BIOMARKERS FOR USE IN INTEGRIN THERAPY APPLICATIONS |
摘要 |
The present invention relates to biomarkers for use in determining the sensitivity of patients to therapy with αv&bgr;6 integrin inhibition or therapy with TGF-&bgr; pathway inhibitors. The biomarker profiles disclosed herein provide individualized gene and protein profiles which will aid in treating diseases and disorders which are amenable to treatment with therapies designed against αv&bgr;6-integrin and/or TGF-&bgr; pathway inhibitors. |
申请公布号 |
EP2831104(A4) |
申请公布日期 |
2015.09.16 |
申请号 |
EP20130768248 |
申请日期 |
2013.03.15 |
申请人 |
BIOGEN MA INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
VIOLETTE, SHELIA M.;SHEPPARD, DEAN |
分类号 |
C07K14/495;G01N33/68 |
主分类号 |
C07K14/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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