| 发明名称 | Process for the preparation of acebrophylline | ||
| 摘要 | The present invention relates to an improved process for preparing Acebrophylline comprising preparing a reaction mixture of theophylline-7-acetate and ambroxol base in a non-polar solvent; heating said reaction mixture at a suitable temperature; and isolating Acebrophylline by filtration. The yield of Acebrophylline is between 95-98% with a purity of 99%. | ||
| 申请公布号 | US9133196(B2) | 申请公布日期 | 2015.09.15 |
| 申请号 | US201314352168 | 申请日期 | 2013.02.07 |
| 申请人 | AMI LIFESCIENCES PVT. LTD. | 发明人 | Patel Kalpesh Ravajibhai;Thakrar Virendra Haridasbhai;Dodiya Dipti Kishorbhai;Solanki Sharad Kanabhai;Shah Kinchit Jitendrakumar |
| 分类号 | C07D473/08;C07C213/08 | 主分类号 | C07D473/08 |
| 代理机构 | Nixon & Vanderhye P.C. | 代理人 | Nixon & Vanderhye P.C. |
| 主权项 | 1. A process for preparing Acebrophylline comprising: (a) preparing a reaction mixture of theophylline-7-acetic acid and ambroxol base in non-polar solvent; (b) heating said reaction mixture at a suitable temperature; and (c) isolating Acebrophylline by filtration. | ||
| 地址 | Gujarat, Baroda IN | ||