Maintenance therapy regime/regimen for the treatment of acne

摘要

A novel maintenance therapy regime/regimen for the treatment of acne related diseases includes administering an oral antibiotic with a topical fixed-dose combination of a retinoid, such as adapalene, and an anti-bacterial agent, such as benzoyl peroxide.

主权项

1. A maintenance therapy regime/regimen for inhibiting or treating moderate to severe acne vulgaris comprising:
(a) first orally administering to a subject in need of such treatment a therapeutically effective amount of an oral antibiotic which is doxycycline hyclate for a first predetermined period of time of 4 weeks; and (b) subsequent to the first predetermined period of time of 4 weeks topically applying onto the affected skin area of the subject in need of such treatment, a therapeutically effective amount of a fixed-dose combination which comprises at least one retinoid which is adapalene and at least one topical antibacterial agent which is benzoyl peroxide for a second predetermined period of time of 24 weeks.