发明名称 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
摘要 A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.
申请公布号 US9132211(B2) 申请公布日期 2015.09.15
申请号 US201414254160 申请日期 2014.04.16
申请人 The Spectranetics Corporation 发明人 Michal Eugene T.;Pollman Matthew J.
分类号 A61L29/08;A61L29/16;A61L33/00;A61L29/14;A61M25/10 主分类号 A61L29/08
代理机构 Carter DeLuca Farrell & Schmidt LLP 代理人 Carter DeLuca Farrell & Schmidt LLP
主权项 1. A medical device coating comprising: poly(hydroxyethyl methacrylic) acid complexed with iodine; and a substantially water-insoluble therapeutic agent dispersed in the poly(hydroxyethyl methacrylic) acid complexed with the iodine.
地址 Colorado Springs CO US