发明名称 |
Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
摘要 |
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue. |
申请公布号 |
US9132211(B2) |
申请公布日期 |
2015.09.15 |
申请号 |
US201414254160 |
申请日期 |
2014.04.16 |
申请人 |
The Spectranetics Corporation |
发明人 |
Michal Eugene T.;Pollman Matthew J. |
分类号 |
A61L29/08;A61L29/16;A61L33/00;A61L29/14;A61M25/10 |
主分类号 |
A61L29/08 |
代理机构 |
Carter DeLuca Farrell & Schmidt LLP |
代理人 |
Carter DeLuca Farrell & Schmidt LLP |
主权项 |
1. A medical device coating comprising:
poly(hydroxyethyl methacrylic) acid complexed with iodine; and a substantially water-insoluble therapeutic agent dispersed in the poly(hydroxyethyl methacrylic) acid complexed with the iodine. |
地址 |
Colorado Springs CO US |