摘要 |
The present invention relates to compounds of Formula (I) (see formula I) ;wherein X1, X2, X3, X4, X5, X6, X7, X8, R1, R2, R3, are as defined above. The compounds have apoptosis signal-regulating kinase ("ASK 1") inhibitory activity. The invention also relates to pharmaceutical compositions comprising one or more of the compounds of Formula (I), and to methods of preparing the compounds of Formula (I). |