Analysis of the methylation pattern of the alpha-synuclein gene from DNA of peripheral blood monocytes for diagnosing Parkinson's disease

摘要

The invention pertains to the use of DNA from peripheral blood monocytes for determining the methylation pattern of the SNCA gene in diagnosing and/or assessing a patient's risk of developing Parkinson's disease, and further provides a method of determining the methylation pattern of the human SNCA gene for diagnosing and/or assessing a patient's risk of developing Parkinson's disease, wherein the SNCA gene is obtained from DNA of peripheral blood monocytes of said patient.