| 摘要 |
Novel compounds of the general formula;
are introduced, containing 5-arylidene-3,5-dihydro-4h-imidazol-4-one core. These compounds can be used for fluorescent staining of cell membranes, biomolecules' labeling in vivo and in vitro, a number of compounds also have photoacidic properties. This allows to use them, for example, as instruments to drastically change pH of a medium, and also as dynamic fluorescent probes for investigation of complex objects like proteins and micellae, as well as in studies of hydration dynamics and in photolithography. |
| 主权项 |
1. A compound of the formula (I):where
A is selected from linear or branched C1-6 alkyl or C4-6 cycloalkyl, D is selected from aryl, heteroaryl, or may be absent, X is selected from hydrogen, halogen, unsubstituted or C1-6 alkyl substituted aminogroup, in which substituents not necessarily form cyclic substituted pyrrol or pyrrolidine derivatives, or C4-6 cycloalkyl substituted aminogroup, azide, isothiocyanate, isocyanate, alcohol or thiol group, acethylene fragment, carboxyl group, or may be absent, Y is independently selected from fluorine, hydroxyl or alkoxyl group with C1-6 alkyl substituent, R1, R2, R3, R4 are independently selected from hydrogen, halogen, unsubstituted or C1-6 alkyl substituted aminogroup, in which substituents not necessarily form cyclic substituted pyrrol or pyrrolidine derivatives, or C4-6 cycloalkyl substituted aminogroup, hydroxyl or C1-6 alkyl alkoxyl group, and also its salts and/or stereoisomers. |
