发明名称 |
Composite lacrimal insert and related methods |
摘要 |
Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed. |
申请公布号 |
US9132088(B2) |
申请公布日期 |
2015.09.15 |
申请号 |
US200912432553 |
申请日期 |
2009.04.29 |
申请人 |
Mati Therapeutics Inc. |
发明人 |
Sim Sylvie;Jain Rachna;Farinas Kathleen |
分类号 |
A61K9/00;A61K47/34;A61F9/00 |
主分类号 |
A61K9/00 |
代理机构 |
Mati Therapeutics Inc |
代理人 |
Anderson Koren;Mati Therapeutics Inc |
主权项 |
1. A lacrimal implant configured to be inserted into a lacrimal canaliculus of a patient comprising:
a unitary implant body, including first and second portions defining a single longitudinal axis, wherein the unitary body is formed from a substantially non-swelling polymer comprising one or more of a polyurethane polymer, a polyurethane copolymer, or silicone, the first portion extending from a proximal end of the implant body, the first portion having a first diameter, wherein the first portion includes a cavity extending inward from the proximal end of the first portion, the cavity having a first supply of a first active agent for release to the eye when the lacrimal implant is implanted at least partially into the lacrimal canaliculus of the patient, and the second portion comprising a distal end portion of the implant body and extending from a distal end of the first portion, the second portion having a second diameter less than the first diameter; and an expandable retention member fully enveloping the second portion of the implant body, the expandable retention member configured to swell via absorption of an aqueous medium after insertion into the lacrimal canaliculus so as to retain the implant body within the lacrimal canaliculus. |
地址 |
Austin TX US |