| 发明名称 | Antibody treatment of Alzheimer's and related diseases | ||
| 摘要 | Provided is an antibody that selectively binds to an epitope formed by residues 1-11 of Aβ in an Aβ oligomer, a method comprising using the antibody to treat a disease characterized by such an Aβ amyloid deposit in a patient, and kits comprising same. | ||
| 申请公布号 | US9133267(B2) | 申请公布日期 | 2015.09.15 |
| 申请号 | US200612085427 | 申请日期 | 2006.11.21 |
| 申请人 | The Trustees of The University of Pennsylvania | 发明人 | Lee Virginia Man-Yee;Lee Edward;Trojanowski John Q. |
| 分类号 | A61K39/395;C07K16/18;G01N33/577;G01N33/53 | 主分类号 | A61K39/395 |
| 代理机构 | Saul Ewing LLP | 代理人 | Saul Ewing LLP ;Doyle Kathryn;Silva Domingos J. |
| 主权项 | 1. An isolated murine antibody that selectively binds to an epitope comprising residues 1-11 of human Aβ in an Aβ oligomer and does not recognize neurofibrillary tangles or Lewy bodies, wherein the antibody is monoclonal antibody NAB61. | ||
| 地址 | Philadelphia PA US | ||