Methods for diagnosing and treating cancers

摘要

This disclosure provides methods and compositions for inhibiting immune responses. The disclosure also provides methods and compositions for inhibiting graft rejection and promoting or prolonging graft survival.

主权项

1. A method for detecting whether a subject has a neoplasia of a tissue type selected from endometrium, kidney, stomach, pancreas, and uterus, comprising:
(a) selecting a subject from a population, wherein the subject is suspected of harboring a neoplasia of a tissue type selected from endometrium, kidney, stomach, pancreas, and uterus; (b) obtaining a biological sample from said subject; and (c) detecting in the biological sample a ColoUp2 polypeptide, wherein the ColoUp2 polypeptide is encoded by a nucleic acid sequence that is at least 95% identical to the nucleic acid sequence of SEQ ID NO: 2.