发明名称 |
Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers |
摘要 |
The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumor immune responses against gastric cancers (GC). |
申请公布号 |
US9132177(B2) |
申请公布日期 |
2015.09.15 |
申请号 |
US201113051568 |
申请日期 |
2011.03.18 |
申请人 |
IMMATICS BIOTECHNOLOGIES GMBH |
发明人 |
Fritsche Jens;Weinschenk Toni;Walter Steffen;Lewandrowski Peter;Singh Harpreet |
分类号 |
A61K38/04;A61K39/39;C07K7/00;A61K39/00;C07K14/47 |
主分类号 |
A61K38/04 |
代理机构 |
Miles and Stockbridge |
代理人 |
Miles and Stockbridge |
主权项 |
1. A pharmaceutical composition, comprising at least two peptides, wherein said at least two peptides are HLA-A*024 ligands consisting of an amino acid sequence according to SEQ ID NO: 1 and SEQ ID NO: 2, and wherein said peptides are in the form of a pharmaceutically acceptable salt. |
地址 |
Teubingen DE |