发明名称 METHODS FOR MANAGING CARE OF PATIENTS PREDISPOSED TO PROGRESSIVE MITRAL VALVE DISEASES
摘要 The present invention relates to methods for treating or preventing a mitral valve disease in a subject in need thereof, comprising administering to the subject an effective amount of a therapeutic agent. The therapeutic agent is capable of suppressing serotonin receptor signaling. The methods may be combined with a mitral valve surgery, serotonin transporter polymorphism genotyping, MV disease diagnosis, and/or an adjunct assay. Also provided are related medicaments, pharmaceutical compositions, and methods for preparing the medicaments.
申请公布号 CA2941686(A1) 申请公布日期 2015.09.11
申请号 CA20152941686 申请日期 2015.03.03
申请人 THE CHILDREN'S HOSPITAL OF PHILADELPHIA;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 LEVY, ROBERT J.;FERRARI, GIOVANNI
分类号 A61K31/495 主分类号 A61K31/495
代理机构 代理人
主权项
地址