ANTICANCER FUSION PROTEIN

摘要

A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence which fragment begins with an amino acid at a position not lower than hTRAIL95 or a homolog of said functional fragment having at least 70% sequence identity preferably 85% identity and ending with the amino acid hTRAIL281; and domain (b) which is a sequence of an effector peptide inhibiting protein synthesis wherein the sequence of domain (b) is attached at the C terminus or N terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.