| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to biotechnology. Disclosed are methods and compositions for the cancer detection in an individual and the treatment efficacy assessment in the same individual. What is disclosed is a method for using a polymerase chain reaction with reverse transcription (RT-PCR) and a multiplex chain reaction, as well as a template exchange and extension reaction for detecting point mutations, truncation and fusion of anaplastic lymphoma kinase.EFFECT: presented group of inventions can be used in medicine.24 cl, 6 dwg, 3 tbl, 5 ex |
