| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to biotechnology, gene engineering and immunology. There are disclosed HIV-1 gp41 binding single-chain triple-stranded alpha-coiled supercoiled molecules denoted as Alphabodies. There are also described nucleic acids coding the said Alphabodies, host cells containing the above nucleic acids, as well as pharmaceutical compositions containing the said Antibodies.EFFECT: presented group of inventions can be used in medicine for treating, preventing and diagnosing HIV-infection.16 cl, 16 dwg, 3 ex |
