Coating for Cells, Reagents and Methods

摘要

The disclosure provides coated mammalian cells, and related reagents, as well as methods for coating mammalian cells, and methods for implanting the coated cells into a human host.

主权项

1. A polymeric capsule that is capable of encapsulating at least one mammalian cell,
the polymeric capsule comprising a polymer that comprises a plurality of monomer units, wherein the polymer comprises a C2-C3 linked polyether of a 1,6:2,3-dianhydrohexopyranose, wherein the plurality of monomer units comprises a monomeric unit that is structure A of FIG. 34, a monomeric unit that is structure B of FIG. 34, or a monomeric unit that is structure C of FIG. 34, or any combination of said monomeric units, wherein the capsule exhibits reverse thermal gelation properties in aqueous media.