| 发明名称 |
MANUFACTURE OF 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID |
| 摘要 |
Described herein are certain processes for the synthesis of compounds of Formula (I): |
| 申请公布号 |
US2015252010(A1) |
申请公布日期 |
2015.09.10 |
| 申请号 |
US201314409806 |
申请日期 |
2013.07.02 |
| 申请人 |
ARDEA BIOSCIENCES, INC. |
发明人 |
Gunic Esmir;Galvin Gabriel |
| 分类号 |
C07D249/12 |
主分类号 |
C07D249/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for preparing a compound of formula (III): comprising contacting a compound of Formula (II): wherein R is —C1-C20 alkyl, —C1-C20 alkenyl, —C3-C10 cycloalkyl, or —C3-C10 cycloalkenyl; with N-bromosuccinimide (NBS) and a solvent. |
| 地址 |
San Diego CA US |
