METHODS FOR SYNTHESIS OF DIHYDROPYRIDOPHTHALAZINONE DERIVATIVES

摘要

FIELD: chemistry.SUBSTANCE: invention relates to a method of producing a compound of formulaand a salt thereof, which includes reacting a compound of formulaor a salt thereof with a hydrazine monohydrate, where R is C-Calkyl; where the compound of formula (5) or a salt thereof is obtained by reacting a compound of formulaor a salt thereof with 4-fluorobenzaldehyde in the presence of a reducing agent and an acid or a Lewis acid, where R is C-Calkyl. The invention also relates to alternative methods of producing a compound of formula (1) and to intermediate compounds whose structural formulae are given in the claim.EFFECT: obtaining a compound of formula (1) using novel methods with improved output and obtaining novel intermediate compounds.47 cl, 14 ex