| 摘要 |
<p>[TASK] To provide a transdermal patch containing the rivastigmine that thoroughly obtains desired adhesive properties, that has good temporal stability of the rivastigmine without using an anti-oxidizing agent, and can be easily produced with a reduced production cost. [MEANS OF SOLVING THE PROBLEM] A transdermal patch for the treatment of Alzheimer's disease includes: a backing, a rivastigmine-containing layer, a pressure-sensitive adhesive layer, and a release liner. In the transdermal patch, the rivastigmine-containing layer contains rivastigmine and an alkyl (meth)acrylate resin, the pressure-sensitive adhesive layer is composed of an acrylic pressure-sensitive adhesive containing a (meth)acrylic acid ester having a hydroxy group, and neither the rivastigmine-containing layer nor the pressure-sensitive adhesive layer contains an anti-oxidizing agent.</p> |
