摘要 |
PROBLEM TO BE SOLVED: To provide therapeutic agents for visceral pain.SOLUTION: The invention provides a method for treating visceral pain or conditions caused by the action of nitrogen monoxide synthetase or the action of serotonin 5HT1D/1B receptor in mammals, which method comprises administration of an indole compound of Formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein in the Formula (I), Ris H or substituted/unsubstituted C1-6 alkyl; Rand Rare independently H, Hal etc.; Rand Rare independently H, F etc.; Ris H, RC(NH)NH etc.; Ris substituted/unsubstituted C1-6 alkyl or substituted/unsubstituted C2-9 heterocyclyl; Ris H, F etc. |