发明名称 INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN
摘要 PROBLEM TO BE SOLVED: To provide therapeutic agents for visceral pain.SOLUTION: The invention provides a method for treating visceral pain or conditions caused by the action of nitrogen monoxide synthetase or the action of serotonin 5HT1D/1B receptor in mammals, which method comprises administration of an indole compound of Formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein in the Formula (I), Ris H or substituted/unsubstituted C1-6 alkyl; Rand Rare independently H, Hal etc.; Rand Rare independently H, F etc.; Ris H, RC(NH)NH etc.; Ris substituted/unsubstituted C1-6 alkyl or substituted/unsubstituted C2-9 heterocyclyl; Ris H, F etc.
申请公布号 JP2015157826(A) 申请公布日期 2015.09.03
申请号 JP20150075893 申请日期 2015.04.02
申请人 NEURAXON INC 发明人 SHAWN MADDAFORD;JAILALL RAMNAUTH;SUMAN RAKHIT;JOANNE PATMAN;PAUL RENTON;SABHASH C ANNEDI;JOHN S ANDREWS;GABRIELA MLADENOVA
分类号 A61K31/437;A61K31/4045;A61K31/439;A61K31/4439;A61K31/454;A61K31/485;A61K31/5377;A61K45/00;A61P9/06;A61P9/10;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/36;A61P29/00;A61P43/00;C07D403/04;C07D409/12;C07D409/14 主分类号 A61K31/437
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