发明名称 |
ANTIVIRAL COMPOUND |
摘要 |
PROBLEM TO BE SOLVED: To provide an antiviral compound.SOLUTION: In one embodiment the invention provides a compound of the invention which is a compound of formula (I): J-Y-J (I) as described herein, or a pharmaceutically acceptable salt, or a prodrug thereof. The invention also provides isotopically enriched compounds that are compounds of formula I that comprise an enriched isotope at one or more positions in the compound. The present invention also provides a pharmaceutical composition comprising a compound of the invention and at least one pharmaceutically acceptable carrier. The present invention also provides a pharmaceutical composition for use in treating disorders associated with HCV. The present invention also provides a pharmaceutical composition further comprising an interferon or pegylated interferon. |
申请公布号 |
JP2015157842(A) |
申请公布日期 |
2015.09.03 |
申请号 |
JP20150091474 |
申请日期 |
2015.04.28 |
申请人 |
GILEAD PHARMASSET LLC |
发明人 |
GUO HONGYAN;DARRYL KATO;THORSTEN A KIRSCHBERG;LIU HONGTAO;JOHN O LINK;MICHAEL L MITCHELL;JAY P PARRISH;NEIL SQUIRES;SUN JIANYU;JAMES TAYLOR;ELIZABETH M BACON;EDA CANALES;CHO AESOP;KIM CHOUNG U;JEROMY J COTTELL;DESAI MANOJ C;RANDALL L HALCOMB;EVAN S KRYGOWSKI;SCOTT E LAZERWITH;LIU QI;RICHARD MACKMANN;HYUNG-JUNG PYUN;JOSEPH H SAUGIER;JAMES D TRENKLE;TSE WINSTON C;VIVIAN RANDALL W;SCOTT D SCHROEDER;WATKINS WILLIAM J;XU LIANHONG;YANG ZHENG-YU;TERRY KELLAR;SHENG XIAONING;MICHAEL O'NEIL HANRAHAN CLARKE;CHOU CHIEN-HUNG;MICHAEL GRAUPE;HAOLUN JIN;RYAN MCFADDEN;MICHAEL R MISH;SAMUEL E METOBO;BARTON W PHILLIPS;CHANDRASEKAR VENKATARAMANI |
分类号 |
C07D401/14;A61K31/4178;A61K31/4184;A61K31/427;A61K31/437;A61K31/438;A61K31/4439;A61K31/454;A61K31/4709;A61K31/496;A61K31/4985;A61K31/5377;A61K31/5415;A61K31/55;A61K31/7056;A61K31/7068;A61K38/21;A61K45/00;A61P1/16;A61P31/14;A61P43/00;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D417/14;C07D471/04;C07D471/10;C07D487/04;C07D491/113;C07D493/06;C07D495/04 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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地址 |
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