Protein involved in ovarian cancer

摘要

The present invention relates to new uses of CDCP1 in the diagnosis, screening, treatment and prophylaxis of ovarian cancer. The invention also provides compositions comprising CDCP1, including vaccines, antibodies that are immunospecific for CDCP1 and agents which interact with or modulate the expression or activity of CDCP1 or which modulate the expression of the nucleic acid which codes for CDCP1.

主权项

1. A method of screening for and/or diagnosis or prognosis of ovarian cancer in a human female subject, and/or monitoring the effectiveness of ovarian cancer therapy, which comprises the steps of
(a) detecting and/or quantifying in an ovarian tissue sample obtained from said subject, the expression of a CDCP 1 polypeptide using an immunoassay; and (b) comparing the level of expression of CDCP 1 in the sample with a previously determined reference range or control.