| 发明名称 |
ENANTIOPURE TETRASUBSTITUTED PYRROLIDINES AS SCAFFOLDS FOR PROTEASOME INHIBITORS AND MEDICINAL APPLICATIONS THEREOF |
| 摘要 |
<p>The present invention refers to compounds of general formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and the use thereof for the treatment and/or chemoprevention of cancer, hematological malignancy, proliferative diseases, autoimmune diseases, neurodegenerative diseases and viral infections.</p> |
| 申请公布号 |
WO2015124663(A1) |
申请公布日期 |
2015.08.27 |
| 申请号 |
WO2015EP53483 |
申请日期 |
2015.02.19 |
| 申请人 |
IKERCHEM, S.L.;UNIVERSIDAD DEL PAÍS VASCO |
发明人 |
COSSÍO MORA, FERNANDO PEDRO;RETAMOSA HERNÁNDEZ, MARÍA DE GRACIA;LARUMBE GÁRATA, AMAIA;ZUBIA OLASCOAGA, AIZPEA;BELLO IGLESIAS, TAMARA;VARA SALAZAR, YOSU ION;MASDEU MARGALEF, MARÍA DEL CARMEN;ALDABA ARÉVALO, ENEKO |
| 分类号 |
C07F5/02;A61K31/69;A61P35/00 |
主分类号 |
C07F5/02 |
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