| 发明名称 |
POLYPEPTIDE EXPRESSION IN CILIATES |
| 摘要 |
This invention is directed to methods for recombinant polypeptide production and, in particular, methods and products for the production of recombinant polypeptides in ciliates. |
| 申请公布号 |
US2015240248(A1) |
申请公布日期 |
2015.08.27 |
| 申请号 |
US201414197109 |
申请日期 |
2014.03.04 |
| 申请人 |
Tetragenetics, Inc. |
发明人 |
COLUSSI Paul;CASSIDY-HANLEY Donna;CLARK Theodore G. |
| 分类号 |
C12N15/79;C12P21/02 |
主分类号 |
C12N15/79 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleic acid construct comprising:
a) a selection cassette encoding a resistance marker, b) a transgene cassette encoding a recombinant polypeptide, and c) a C3 allele rDNA locus comprising a 17S rDNA gene that does not confer paromomycin resistance to a ciliate transformed with the nucleic acid construct. |
| 地址 |
Cambridge MA US |
