Integrin alphavbeta8 neutralizing antibody

摘要

The present invention relates to α&ngr;&bgr;8 antagonists, anti-α&ngr;&bgr;8 antibodies or immunoconjugates for reducing &Tgr;GF&bgr; activation in an individual. Further provided are compositions comprising one of the α&ngr;&bgr;8 antagonists, anti-α&ngr;&bgr;8 antibodies or immunoconjugates, methods for using the compositions, and related subject matter.