| 发明名称 | Preparation method of micafungin sodium | ||
| 摘要 | The method of the preparation of micafungin sodium comprises the step of mixing the weak base and the aqueous solution containing micafungin acid (the structure is illustrated by formula I) or the mixed aqueous solution containing the compound of formula I and organic solvent in order to obtain the sodium salt of micafungin (the structure is illustrated by formula II).; | ||
| 申请公布号 | US9115177(B2) | 申请公布日期 | 2015.08.25 |
| 申请号 | US201214116947 | 申请日期 | 2012.05.11 |
| 申请人 | Shanghai Techwell Biopharmaceutical Co., Ltd. | 发明人 | Jiao Guangjun;Liu Shidong;He Bingming;Tang Zhijun;Ji Xiaoming |
| 分类号 | C07K1/113;C07K7/56;C07K1/14;C07D413/12 | 主分类号 | C07K1/113 |
| 代理机构 | Weaver Austin Villeneuve & Sampson LLP | 代理人 | Hunter Tom;Weaver Austin Villeneuve & Sampson LLP |
| 主权项 | 1. A method for the preparation of the compound of formula II, wherein said method comprises: mixing a weak base solution with a water solution containing the compound of formula I or a mixture solution of water and organic solvent(s) containing the compound of formula Ito obtain the compound of formula II: | ||
| 地址 | Shanghai CN | ||