| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to compounds of formula I or their pharmaceutically acceptable salts. Compounds by invention possess properties of JAK2 kinase inhibitors. In formula IRrepresents phenyl, optionally substituted with 1-3 R; Rrepresents phenyl, optionally substituted with 1-2 R; R, Rand Rindependently represent H. values of the rest of radicals are presented in invention formula. Invention also relates to particular compounds, structural formulae of which are presented in invention formula.EFFECT: novel compounds, possessing properties of JAK2 kinase inhibitor have been obtained.11 cl, 2 tbl, 312 ex |
